Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2218658..2218875 Replicon chromosome
Accession NZ_LR130513
Organism Staphylococcus aureus strain BPH2900 isolate BPH2900

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag EW029_RS11390 Protein ID WP_075583739.1
Coordinates 2218771..2218875 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2218658..2218713 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW029_RS11370 2214780..2215445 - 666 WP_001024097.1 SDR family oxidoreductase -
EW029_RS11375 2215597..2215917 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EW029_RS11380 2215919..2216899 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
EW029_RS11385 2217165..2218256 + 1092 WP_000495678.1 hypothetical protein -
- 2218658..2218713 + 56 - - Antitoxin
EW029_RS11390 2218771..2218875 - 105 WP_075583739.1 hypothetical protein Toxin
EW029_RS11395 2218973..2219134 - 162 Protein_2126 helix-turn-helix domain-containing protein -
EW029_RS11405 2219552..2219710 + 159 WP_024928151.1 hypothetical protein -
EW029_RS11415 2220370..2221227 - 858 WP_000370944.1 Cof-type HAD-IIB family hydrolase -
EW029_RS11420 2221295..2222077 - 783 WP_000908181.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3861.73 Da        Isoelectric Point: 7.0039

>T286157 WP_075583739.1 NZ_LR130513:c2218875-2218771 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT286157 NZ_LR130513:2218658-2218713 [Staphylococcus aureus]
AAAAAGGGCAACACTCAGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References