Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2116731..2116993 Replicon chromosome
Accession NZ_LR130509
Organism Staphylococcus aureus strain BPH2760 isolate BPH2760

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag EW032_RS10825 Protein ID WP_001802298.1
Coordinates 2116889..2116993 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2116731..2116894 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW032_RS10805 2112980..2113645 - 666 WP_001024105.1 SDR family oxidoreductase -
EW032_RS10810 2113797..2114117 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
EW032_RS10815 2114119..2115099 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
EW032_RS10820 2115365..2116456 + 1092 WP_000495683.1 hypothetical protein -
- 2116731..2116894 + 164 - - Antitoxin
EW032_RS10825 2116889..2116993 - 105 WP_001802298.1 hypothetical protein Toxin
EW032_RS10835 2117673..2117831 + 159 WP_001792784.1 hypothetical protein -
EW032_RS10845 2118490..2119347 - 858 WP_000370917.1 Cof-type HAD-IIB family hydrolase -
EW032_RS10850 2119415..2120197 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T286128 WP_001802298.1 NZ_LR130509:c2116993-2116889 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 164 bp

>AT286128 NZ_LR130509:2116731-2116894 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References