Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1825314..1825496 Replicon chromosome
Accession NZ_LR130509
Organism Staphylococcus aureus strain BPH2760 isolate BPH2760

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag EW032_RS09105 Protein ID WP_001801861.1
Coordinates 1825314..1825409 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1825437..1825496 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EW032_RS09055 1820984..1821610 + 627 WP_000669017.1 hypothetical protein -
EW032_RS09060 1821651..1821992 + 342 WP_000627541.1 DUF3969 family protein -
EW032_RS09065 1822093..1822665 + 573 WP_000414202.1 hypothetical protein -
EW032_RS09070 1822863..1823420 - 558 Protein_1700 ImmA/IrrE family metallo-endopeptidase -
EW032_RS09080 1823794..1823970 - 177 WP_000375477.1 hypothetical protein -
EW032_RS09085 1823981..1824364 - 384 WP_000070811.1 hypothetical protein -
EW032_RS09095 1824968..1825111 - 144 WP_001549059.1 transposase -
EW032_RS09105 1825314..1825409 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1825437..1825496 - 60 - - Antitoxin
EW032_RS09110 1825532..1825633 + 102 WP_001791893.1 hypothetical protein -
EW032_RS09115 1825611..1825787 - 177 Protein_1706 transposase -
EW032_RS09120 1825981..1826358 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T286124 WP_001801861.1 NZ_LR130509:1825314-1825409 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

Antitoxin


Download         Length: 60 bp

>AT286124 NZ_LR130509:c1825496-1825437 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References