Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2423994..2424257 Replicon chromosome
Accession NZ_LR027878
Organism Staphylococcus aureus strain BPH2003 isolate BPH2003

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag E0E10_RS12890 Protein ID WP_001802298.1
Coordinates 2424153..2424257 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2423994..2424158 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0E10_RS12870 2420177..2420842 - 666 WP_001024094.1 SDR family oxidoreductase -
E0E10_RS12875 2420994..2421314 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
E0E10_RS12880 2421316..2422296 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
E0E10_RS12885 2422562..2423653 + 1092 WP_000495671.1 lytic regulatory protein -
- 2423994..2424158 + 165 - - Antitoxin
E0E10_RS12890 2424153..2424257 - 105 WP_001802298.1 hypothetical protein Toxin
E0E10_RS16355 2424418..2424901 - 484 Protein_2389 recombinase family protein -
E0E10_RS12900 2424944..2426080 - 1137 WP_000115564.1 SAP domain-containing protein -
E0E10_RS12905 2426369..2426461 + 93 WP_001790138.1 hypothetical protein -
E0E10_RS12910 2427166..2428023 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
E0E10_RS12915 2428091..2428873 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T286097 WP_001802298.1 NZ_LR027878:c2424257-2424153 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT286097 NZ_LR027878:2423994-2424158 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAGTAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References