Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2598337..2598521 Replicon chromosome
Accession NZ_LR027877
Organism Staphylococcus aureus isolate BPH3244

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag E0E14_RS13715 Protein ID WP_000482650.1
Coordinates 2598414..2598521 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2598337..2598397 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0E14_RS13690 2593867..2594034 - 168 WP_001790576.1 hypothetical protein -
E0E14_RS13700 2594265..2595998 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
E0E14_RS13705 2596023..2597786 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2598337..2598397 + 61 - - Antitoxin
E0E14_RS13715 2598414..2598521 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
E0E14_RS13720 2598654..2599040 - 387 WP_000779358.1 flippase GtxA -
E0E14_RS13725 2599308..2600450 + 1143 WP_001176863.1 glycerate kinase -
E0E14_RS13730 2600510..2601169 + 660 WP_000831298.1 membrane protein -
E0E14_RS13735 2601351..2602562 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
E0E14_RS13740 2602685..2603158 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T286083 WP_000482650.1 NZ_LR027877:c2598521-2598414 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT286083 NZ_LR027877:2598337-2598397 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References