Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1905089..1905271 Replicon chromosome
Accession NZ_LR027877
Organism Staphylococcus aureus isolate BPH3244

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag E0E14_RS09575 Protein ID WP_001801861.1
Coordinates 1905089..1905184 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1905212..1905271 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0E14_RS09525 1900749..1901375 + 627 WP_000669046.1 hypothetical protein -
E0E14_RS09530 1901416..1901760 + 345 WP_000627551.1 DUF3969 family protein -
E0E14_RS09535 1901858..1902409 + 552 WP_000414205.1 hypothetical protein -
E0E14_RS09540 1902627..1903268 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
E0E14_RS09545 1903382..1903567 - 186 WP_000809857.1 hypothetical protein -
E0E14_RS09550 1903569..1903745 - 177 WP_000375476.1 hypothetical protein -
E0E14_RS09555 1903756..1904139 - 384 WP_000070811.1 hypothetical protein -
E0E14_RS09565 1904743..1904886 - 144 WP_001549059.1 transposase -
E0E14_RS09575 1905089..1905184 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1905212..1905271 - 60 - - Antitoxin
E0E14_RS09580 1905307..1905408 + 102 WP_001791893.1 hypothetical protein -
E0E14_RS09585 1905386..1905562 - 177 Protein_1801 transposase -
E0E14_RS09590 1905756..1906133 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T286071 WP_001801861.1 NZ_LR027877:1905089-1905184 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

Antitoxin


Download         Length: 60 bp

>AT286071 NZ_LR027877:c1905271-1905212 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References