Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2595055..2595239 Replicon chromosome
Accession NZ_LR027876
Organism Staphylococcus aureus strain JKD6009 isolate JKD6009

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag E0E12_RS13810 Protein ID WP_000482650.1
Coordinates 2595132..2595239 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2595055..2595115 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0E12_RS13785 2590585..2590752 - 168 WP_001790576.1 hypothetical protein -
E0E12_RS13795 2590983..2592716 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
E0E12_RS13800 2592741..2594504 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2595055..2595115 + 61 - - Antitoxin
E0E12_RS13810 2595132..2595239 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
E0E12_RS13815 2595372..2595758 - 387 WP_000779358.1 flippase GtxA -
E0E12_RS13820 2596026..2597168 + 1143 WP_001176863.1 glycerate kinase -
E0E12_RS13825 2597228..2597887 + 660 WP_000831298.1 membrane protein -
E0E12_RS13830 2598069..2599280 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
E0E12_RS13835 2599403..2599876 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T286066 WP_000482650.1 NZ_LR027876:c2595239-2595132 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT286066 NZ_LR027876:2595055-2595115 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References