Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2300706..2300923 Replicon chromosome
Accession NZ_LR027876
Organism Staphylococcus aureus strain JKD6009 isolate JKD6009

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag E0E12_RS12195 Protein ID WP_001802298.1
Coordinates 2300819..2300923 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2300706..2300761 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0E12_RS12175 2296843..2297508 - 666 WP_001024106.1 SDR family oxidoreductase -
E0E12_RS12180 2297660..2297980 + 321 WP_000003760.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
E0E12_RS12185 2297982..2298962 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
E0E12_RS12190 2299228..2300319 + 1092 WP_000495671.1 lytic regulatory protein -
- 2300706..2300761 + 56 - - Antitoxin
E0E12_RS12195 2300819..2300923 - 105 WP_001802298.1 hypothetical protein Toxin
E0E12_RS15480 2301084..2301567 - 484 Protein_2250 recombinase family protein -
E0E12_RS12205 2301610..2302746 - 1137 WP_000115564.1 SAP domain-containing protein -
E0E12_RS12210 2303035..2303127 + 93 WP_001790138.1 hypothetical protein -
E0E12_RS12215 2303832..2304689 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
E0E12_RS12220 2304757..2305539 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T286064 WP_001802298.1 NZ_LR027876:c2300923-2300819 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT286064 NZ_LR027876:2300706-2300761 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References