Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2373706..2373923 Replicon chromosome
Accession NZ_LR027874
Organism Staphylococcus aureus strain BPH2056 isolate BPH2056

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag E0E13_RS12490 Protein ID WP_001802298.1
Coordinates 2373819..2373923 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2373706..2373761 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0E13_RS12470 2369843..2370508 - 666 WP_001024094.1 SDR family oxidoreductase -
E0E13_RS12475 2370660..2370980 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
E0E13_RS12480 2370982..2371962 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
E0E13_RS12485 2372228..2373319 + 1092 WP_000495671.1 lytic regulatory protein -
- 2373706..2373761 + 56 - - Antitoxin
E0E13_RS12490 2373819..2373923 - 105 WP_001802298.1 hypothetical protein Toxin
E0E13_RS15910 2374084..2374567 - 484 Protein_2317 recombinase family protein -
E0E13_RS12500 2374610..2375746 - 1137 WP_000115564.1 SAP domain-containing protein -
E0E13_RS12505 2376035..2376127 + 93 WP_001790138.1 hypothetical protein -
E0E13_RS12510 2376832..2377689 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
E0E13_RS12515 2377757..2378539 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T286048 WP_001802298.1 NZ_LR027874:c2373923-2373819 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT286048 NZ_LR027874:2373706-2373761 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References