286004

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2309300..2309517 Replicon chromosome
Accession NZ_LR027869
Organism Staphylococcus aureus isolate BPH2869

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag E0E09_RS12235 Protein ID WP_001802298.1
Coordinates 2309413..2309517 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2309300..2309355 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0E09_RS12215 2305437..2306102 - 666 WP_001024094.1 SDR family oxidoreductase -
E0E09_RS12220 2306254..2306574 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
E0E09_RS12225 2306576..2307556 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
E0E09_RS12230 2307822..2308913 + 1092 WP_130826628.1 transcriptional regulator -
- 2309300..2309355 + 56 - - Antitoxin
E0E09_RS12235 2309413..2309517 - 105 WP_001802298.1 hypothetical protein Toxin
E0E09_RS15840 2309678..2310161 - 484 Protein_2256 recombinase family protein -
E0E09_RS12245 2310204..2311340 - 1137 WP_000115564.1 SAP domain-containing protein -
E0E09_RS12250 2311629..2311721 + 93 WP_001790138.1 hypothetical protein -
E0E09_RS12255 2312426..2313283 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
E0E09_RS12260 2313351..2314133 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T286004 WP_001802298.1 NZ_LR027869:c2309517-2309413 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT286004 NZ_LR027869:2309300-2309355 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References