Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1481174..1481828 Replicon chromosome
Accession NZ_LR027557
Organism Pseudomonas synxantha strain 10586

Toxin (Protein)


Gene name higB Uniprot ID A0A0D0TQT9
Locus tag KR485_RS06295 Protein ID WP_043046578.1
Coordinates 1481174..1481524 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A0W0N117
Locus tag KR485_RS06300 Protein ID WP_014718915.1
Coordinates 1481514..1481828 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KR485_RS06285 1477933..1479465 + 1533 WP_216091711.1 NADH-quinone oxidoreductase subunit M -
KR485_RS06290 1479473..1480936 + 1464 WP_216091712.1 NADH-quinone oxidoreductase subunit NuoN -
KR485_RS06295 1481174..1481524 + 351 WP_043046578.1 toxin Toxin
KR485_RS06300 1481514..1481828 + 315 WP_014718915.1 XRE family transcriptional regulator Antitoxin
KR485_RS06305 1481887..1482639 - 753 WP_032880612.1 outer membrane beta-barrel protein -
KR485_RS06310 1482765..1483598 - 834 WP_148853515.1 arylamine N-acetyltransferase -
KR485_RS06315 1483719..1483955 + 237 WP_005789137.1 hypothetical protein -
KR485_RS06320 1483986..1484180 - 195 WP_005789138.1 DUF6021 family protein -
KR485_RS06325 1484193..1484372 - 180 WP_005789140.1 hypothetical protein -
KR485_RS06330 1484488..1485009 + 522 WP_032880610.1 DUF3087 family protein -
KR485_RS06335 1485039..1485899 - 861 WP_032880609.1 Dyp-type peroxidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13785.70 Da        Isoelectric Point: 9.7334

>T285985 WP_043046578.1 NZ_LR027557:1481174-1481524 [Pseudomonas synxantha]
MDALFIELPAFERHRKDYLSEELFQGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQSDLTPHHKKALKHMLDREIKARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11755.58 Da        Isoelectric Point: 10.6525

>AT285985 WP_014718915.1 NZ_LR027557:1481514-1481828 [Pseudomonas synxantha]
MKRDIFSELVEGFDALADERQGKITLRNHKVHLNKLAPLTADEVIAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0D0TQT9

Antitoxin

Source ID Structure
AlphaFold DB A0A0W0N117

References