Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 459472..460083 Replicon chromosome
Accession NZ_LN890656
Organism Candidatus Promineofilum breve strain Cfx-K

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag CFX0092_RS19145 Protein ID WP_095045268.1
Coordinates 459472..459753 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CFX0092_RS19150 Protein ID WP_197699976.1
Coordinates 459772..460083 (+) Length 104 a.a.

Genomic Context

CFX0092_RS19140CFX0092_RS19145CFX0092_RS19150CFX0092_RS19155CFX0092_RS19125CFX0092_RS19130CFX0092_RS19135
Location: 457218..459422 (2205 bp)
Type: Others
Protein ID: WP_095045267.1
Location: 459472..459753 (282 bp)
Type: Toxin
Protein ID: WP_095045268.1
Location: 459772..460083 (312 bp)
Type: Antitoxin
Protein ID: WP_197699976.1
Location: 460161..462338 (2178 bp)
Type: Others
Protein ID: WP_095045269.1
Location: 454829..455749 (921 bp)
Type: Others
Protein ID: WP_095045265.1
Location: 455749..456252 (504 bp)
Type: Others
Protein ID: WP_197699975.1
Location: 456328..457062 (735 bp)
Type: Others
Protein ID: WP_157913340.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CFX0092_RS19125454829..455749-921WP_095045265.1GNAT family N-acetyltransferase-
CFX0092_RS19130455749..456252-504WP_197699975.1MaoC family dehydratase-
CFX0092_RS19135456328..457062-735WP_157913340.1class I SAM-dependent methyltransferase-
CFX0092_RS19140457218..459422+2205WP_095045267.1acyl-CoA mutase large subunit family protein-
CFX0092_RS19145459472..459753+282WP_095045268.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CFX0092_RS19150459772..460083+312WP_197699976.1HigA family addiction module antidote proteinAntitoxin
CFX0092_RS19155460161..462338+2178WP_095045269.1methylmalonyl-CoA mutase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(9-83)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11115.66 Da        Isoelectric Point: 9.6833

>T285783 WP_095045268.1 NZ_LN890656:459472-459753 [Candidatus Promineofilum breve]
MIRSFASKETEKLFRRQFSRKLPEDIQRKARIKLEILDAAGRLNDLRIPPSNRLEKLSGDREGQYSIRINSQWRICFKWE
DDAAHDVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12225.36 Da        Isoelectric Point: 9.9441

>AT285783 WP_197699976.1 NZ_LN890656:459772-460083 [Candidatus Promineofilum breve]
MMDKNELLPPIHPGEILLEEFLQPLKISQYRLAKDMGVPVRRINEIVLGKRRITADTALRLARYFGLSERFWMNLQTRYD
LEVEKDRLRDRLEREVKVFAAAI

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References