Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 2316442..2317082 Replicon chromosome
Accession NZ_LN890655
Organism Candidatus Promineofilum breve strain Cfx-K

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag CFX0092_RS09935 Protein ID WP_095043375.1
Coordinates 2316442..2316759 (+) Length 106 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CFX0092_RS09940 Protein ID WP_095044879.1
Coordinates 2316771..2317082 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFX0092_RS09925 2312800..2314005 - 1206 WP_095043373.1 ABC transporter ATP-binding protein -
CFX0092_RS09930 2314418..2316379 + 1962 WP_095043374.1 aldehyde ferredoxin oxidoreductase family protein -
CFX0092_RS09935 2316442..2316759 + 318 WP_095043375.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFX0092_RS09940 2316771..2317082 + 312 WP_095044879.1 helix-turn-helix domain-containing protein Antitoxin
CFX0092_RS09945 2317125..2317511 + 387 WP_095043376.1 nucleotidyltransferase domain-containing protein -
CFX0092_RS09950 2317535..2317678 + 144 WP_157913050.1 DUF2442 domain-containing protein -
CFX0092_RS22180 2317679..2317843 + 165 WP_157913051.1 hypothetical protein -
CFX0092_RS09960 2318045..2319361 + 1317 WP_162292469.1 CAP domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(3-99)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-83)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 12140.24 Da        Isoelectric Point: 10.3493

>T285779 WP_095043375.1 NZ_LN890655:2316442-2316759 [Candidatus Promineofilum breve]
MVIVETKVFTRQIEELLTDEAYKDLQTELVKRPEVGVLIPGGGGLRKMRWGYQGQGKRGGVRVIYYWAAKQKRILMLFIY
PKNVRDNLSPAQLRALRSIVEAEYQ

Download         Length: 318 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11428.98 Da        Isoelectric Point: 6.2304

>AT285779 WP_095044879.1 NZ_LN890655:2316771-2317082 [Candidatus Promineofilum breve]
MSDELFSELLESVREGGAILRGESQGSRRFEIEAPDVKRIREGFALSQSEFAGMLGISIKTLQNWEQGRRTPHGPARVLL
QVASMHPEAIWSVVHAGIQVKES

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References