Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 2316442..2317082 Replicon chromosome
Accession NZ_LN890655
Organism Candidatus Promineofilum breve strain Cfx-K

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag CFX0092_RS09935 Protein ID WP_095043375.1
Coordinates 2316442..2316759 (+) Length 106 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag CFX0092_RS09940 Protein ID WP_095044879.1
Coordinates 2316771..2317082 (+) Length 104 a.a.

Genomic Context

CFX0092_RS09930CFX0092_RS09935CFX0092_RS09940CFX0092_RS09945CFX0092_RS09950CFX0092_RS22180CFX0092_RS09960CFX0092_RS09925
Location: 2314418..2316379 (1962 bp)
Type: Others
Protein ID: WP_095043374.1
Location: 2316442..2316759 (318 bp)
Type: Toxin
Protein ID: WP_095043375.1
Location: 2316771..2317082 (312 bp)
Type: Antitoxin
Protein ID: WP_095044879.1
Location: 2317125..2317511 (387 bp)
Type: Others
Protein ID: WP_095043376.1
Location: 2317535..2317678 (144 bp)
Type: Others
Protein ID: WP_157913050.1
Location: 2317679..2317843 (165 bp)
Type: Others
Protein ID: WP_157913051.1
Location: 2318045..2319361 (1317 bp)
Type: Others
Protein ID: WP_162292469.1
Location: 2312800..2314005 (1206 bp)
Type: Others
Protein ID: WP_095043373.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CFX0092_RS099252312800..2314005-1206WP_095043373.1ABC transporter ATP-binding protein-
CFX0092_RS099302314418..2316379+1962WP_095043374.1aldehyde ferredoxin oxidoreductase family protein-
CFX0092_RS099352316442..2316759+318WP_095043375.1type II toxin-antitoxin system RelE/ParE family toxinToxin
CFX0092_RS099402316771..2317082+312WP_095044879.1helix-turn-helix domain-containing proteinAntitoxin
CFX0092_RS099452317125..2317511+387WP_095043376.1nucleotidyltransferase domain-containing protein-
CFX0092_RS099502317535..2317678+144WP_157913050.1DUF2442 domain-containing protein-
CFX0092_RS221802317679..2317843+165WP_157913051.1hypothetical protein-
CFX0092_RS099602318045..2319361+1317WP_162292469.1CAP domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(3-99)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-83)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 12140.24 Da        Isoelectric Point: 10.3493

>T285779 WP_095043375.1 NZ_LN890655:2316442-2316759 [Candidatus Promineofilum breve]
MVIVETKVFTRQIEELLTDEAYKDLQTELVKRPEVGVLIPGGGGLRKMRWGYQGQGKRGGVRVIYYWAAKQKRILMLFIY
PKNVRDNLSPAQLRALRSIVEAEYQ

Download         Length: 318 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11428.98 Da        Isoelectric Point: 6.2304

>AT285779 WP_095044879.1 NZ_LN890655:2316771-2317082 [Candidatus Promineofilum breve]
MSDELFSELLESVREGGAILRGESQGSRRFEIEAPDVKRIREGFALSQSEFAGMLGISIKTLQNWEQGRRTPHGPARVLL
QVASMHPEAIWSVVHAGIQVKES

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References