Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
| Location | 29674..30320 | Replicon | plasmid 3 |
| Accession | NZ_LN890526 | ||
| Organism | Salmonella enterica subsp. enterica serovar Weltevreden strain 2511STDY5712385 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | - |
| Locus tag | ARA94_RS24740 | Protein ID | WP_057516471.1 |
| Coordinates | 29674..30024 (+) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | ARA94_RS24745 | Protein ID | WP_057516472.1 |
| Coordinates | 30021..30320 (+) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ARA94_RS24715 | 25037..25570 | - | 534 | WP_057516516.1 | tail fiber assembly protein | - |
| ARA94_RS24935 | 25573..26658 | - | 1086 | WP_065314816.1 | hypothetical protein | - |
| ARA94_RS24725 | 26741..27328 | + | 588 | WP_057516631.1 | recombinase family protein | - |
| ARA94_RS24730 | 27654..28487 | + | 834 | WP_057516469.1 | RepA | - |
| ARA94_RS24735 | 29185..29433 | + | 249 | WP_139679659.1 | hypothetical protein | - |
| ARA94_RS24740 | 29674..30024 | + | 351 | WP_057516471.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| ARA94_RS24745 | 30021..30320 | + | 300 | WP_057516472.1 | XRE family transcriptional regulator | Antitoxin |
| ARA94_RS24750 | 30476..30856 | + | 381 | WP_057516473.1 | hypothetical protein | - |
| ARA94_RS24755 | 30928..31200 | + | 273 | WP_057516474.1 | helix-turn-helix domain-containing protein | - |
| ARA94_RS24765 | 31800..32216 | - | 417 | WP_057516476.1 | Rha family transcriptional regulator | - |
| ARA94_RS24775 | 33019..33267 | - | 249 | WP_057516478.1 | hypothetical protein | - |
| ARA94_RS24780 | 33311..33961 | - | 651 | WP_057516479.1 | P-loop NTPase | - |
| ARA94_RS24785 | 34109..34489 | - | 381 | WP_057516480.1 | hypothetical protein | - |
| ARA94_RS24790 | 34584..35243 | - | 660 | WP_057516481.1 | helix-turn-helix domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..47244 | 47244 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 15014.38 Da Isoelectric Point: 12.8644
>T285778 WP_057516471.1 NZ_LN890526:29674-30024 [Salmonella enterica subsp. enterica serovar Weltevreden]
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Download Length: 351 bp
Antitoxin
Download Length: 100 a.a. Molecular weight: 12835.43 Da Isoelectric Point: 12.7956
>AT285778 WP_057516472.1 NZ_LN890526:30021-30320 [Salmonella enterica subsp. enterica serovar Weltevreden]
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Download Length: 300 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|