Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1896571..1897223 Replicon chromosome
Accession NZ_LN890335
Organism Achromobacter xylosoxidans isolate AX_NCIMB_11015_WG

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag BN2877_RS08610 Protein ID WP_155865122.1
Coordinates 1896885..1897223 (-) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag BN2877_RS08605 Protein ID WP_020925696.1
Coordinates 1896571..1896888 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN2877_RS08600 1896008..1896433 - 426 WP_054504346.1 hypothetical protein -
BN2877_RS08605 1896571..1896888 - 318 WP_020925696.1 transcriptional regulator Antitoxin
BN2877_RS08610 1896885..1897223 - 339 WP_155865122.1 toxin Toxin
BN2877_RS08615 1897453..1897961 + 509 Protein_1691 hypothetical protein -
BN2877_RS08620 1898015..1898443 - 429 WP_054446086.1 CopD family protein -
BN2877_RS08625 1898447..1898758 - 312 WP_049054755.1 DUF3817 domain-containing protein -
BN2877_RS08630 1898897..1899853 + 957 WP_197742945.1 helix-turn-helix domain-containing protein -
BN2877_RS08635 1899948..1900280 - 333 WP_155865126.1 hypothetical protein -
BN2877_RS08640 1900863..1901054 + 192 WP_155865128.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1885780..1906597 20817


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(43-102)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13247.19 Da        Isoelectric Point: 10.0510

>T285760 WP_155865122.1 NZ_LN890335:c1897223-1896885 [Achromobacter xylosoxidans]
MKAVFVELPAFARHRGDYLDDDDFRLLQQAMMWRPDAGVVIEGTGGLRKMRFGDPRRGKGKRGGLRVIYYWWDGREQFWL
FSLYDKDEVSDLSGREKRMLKGMLDAEREARR

Download         Length: 339 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12102.95 Da        Isoelectric Point: 10.3044

>AT285760 WP_020925696.1 NZ_LN890335:c1896888-1896571 [Achromobacter xylosoxidans]
MKKKRNLYAEIAEGFDALAAEREGKRTLRTHKVEMNPAPDLTAEELLAIRERLHLSRQVFAHYLRTNPRTLENWEQGRAK
PNAQAALLIRLVEKFPDTVERLAAV

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References