Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2501409..2501932 Replicon chromosome
Accession NZ_LN854556
Organism Staphylococcus aureus strain B155

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag SABB155_RS12640 Protein ID WP_054189905.1
Coordinates 2501409..2501675 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag SABB155_RS12645 Protein ID WP_020977565.1
Coordinates 2501675..2501932 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SABB155_RS12620 2496617..2497804 - 1188 WP_054189907.1 MFS transporter -
SABB155_RS12625 2498198..2498974 - 777 WP_000072151.1 iron export ABC transporter permease subunit FetB -
SABB155_RS12630 2498967..2499629 - 663 WP_025786559.1 ATP-binding cassette domain-containing protein -
SABB155_RS12635 2499979..2501055 - 1077 WP_054189906.1 M42 family metallopeptidase -
SABB155_RS12640 2501409..2501675 - 267 WP_054189905.1 Txe/YoeB family addiction module toxin Toxin
SABB155_RS12645 2501675..2501932 - 258 WP_020977565.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
SABB155_RS12655 2502292..2502747 + 456 WP_000732082.1 DUF1307 domain-containing protein -
SABB155_RS12660 2502915..2504492 - 1578 WP_054189904.1 FMN-binding glutamate synthase family protein -
SABB155_RS12665 2504687..2505436 + 750 WP_054189903.1 hypothetical protein -
SABB155_RS12670 2505660..2506853 - 1194 WP_006191034.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10587.19 Da        Isoelectric Point: 10.1603

>T285706 WP_054189905.1 NZ_LN854556:c2501675-2501409 [Staphylococcus aureus]
MSNYTVKIKNSAKSDLKKITHPYLKKTFIEIVETLKNDPYKITQSFEKLEPKYLERYSRRINHQHRGVYTIDDRNKVVLI
LSAWSHYD

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9796.79 Da        Isoelectric Point: 4.3304

>AT285706 WP_020977565.1 NZ_LN854556:c2501932-2501675 [Staphylococcus aureus]
MIITSPTEARKHFYQLLKNVNNNHEPIYISGNNAENNAVIIGLEDWKSIQETIYLESTGTMDKVREREKDNSGTTNIDDI
DWDNL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References