Detailed information of TA system TA285696

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 963230..963479
• Replicon: chromosome
• Accession: NZ_LN854556
• Organism: Staphylococcus aureus strain B155

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: SABB155_RS04705
• Protein ID: WP_000623369.1
• Coordinates: 963230..963337 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	963332..963479 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SABB155_RS04680	959896..960465	-	570	WP_000287265.1	competence protein ComK	-
SABB155_RS04685	960675..960893	+	219	WP_000876826.1	IDEAL domain-containing protein	-
SABB155_RS04690	960982..961968	-	987	WP_054190346.1	lipoate--protein ligase	-
SABB155_RS04695	962167..962343	+	177	WP_000214898.1	YkvS family protein	-
SABB155_RS04700	962358..962960	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
SABB155_RS04705	963230..963337	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	963332..963479	-	148	-	-	Antitoxin
SABB155_RS04710	963975..964259	+	285	WP_054190345.1	lactococcin 972 family bacteriocin	-
SABB155_RS04715	964303..966267	+	1965	WP_054190344.1	bacteriocin-associated integral membrane family protein	-
SABB155_RS04720	966270..966590	+	321	WP_054190343.1	YxeA family protein	-
SABB155_RS04725	966587..967228	+	642	WP_054190342.1	ABC transporter ATP-binding protein	-
SABB155_RS14205	967316..967606	-	291	WP_077446589.1	hypothetical protein	-
SABB155_RS14210	967747..967884	+	138	WP_077446590.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	958057..959373	1316

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T285696 WP_000623369.1 NZ_LN854556:963230-963337 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 148 bp

>AT285696 NZ_LN854556:c963479-963332 [Staphylococcus aureus]
CAATTAAATAAAAGATATGTTACTATAATAATGTAAAAAGACGACATGCAGGAACATGTCGCCTATTGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTTCTTTAACCATCATTCGTTGTCAAAGTTTGGAAATGATGGTTATTT

Structures

Antitoxin