Detailed information of TA system TA285693

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-SprF2/-
• Location: 652616..652923
• Replicon: chromosome
• Accession: NZ_LN854556
• Organism: Staphylococcus aureus strain B155

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: SABB155_RS14095
• Protein ID: WP_077446684.1
• Coordinates: 652616..652792 (+)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	652782..652923 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SABB155_RS03115	647849..651634	+	3786	WP_000582158.1	hypothetical protein	-
SABB155_RS03120	651624..651776	+	153	WP_001153681.1	hypothetical protein	-
SABB155_RS03125	651823..652110	+	288	WP_001040261.1	hypothetical protein	-
SABB155_RS03130	652168..652464	+	297	WP_000539688.1	DUF2951 domain-containing protein	-
SABB155_RS14095	652616..652792	+	177	WP_077446684.1	putative holin-like toxin	Toxin
-	652782..652923	-	142	-	-	Antitoxin
SABB155_RS03140	653004..653258	+	255	WP_000611512.1	phage holin	-
SABB155_RS03145	653270..654025	+	756	WP_000861038.1	CHAP domain-containing protein	-
SABB155_RS03150	654216..654707	+	492	WP_000919350.1	staphylokinase	-
SABB155_RS14605	655357..655692	+	336	Protein_606	SH3 domain-containing protein	-
SABB155_RS03160	656201..656551	+	351	WP_000702262.1	complement inhibitor SCIN-A	-
SABB155_RS03165	656604..656864	-	261	WP_001791826.1	hypothetical protein	-
SABB155_RS03175	657175..657354	-	180	WP_000669789.1	hypothetical protein	-
SABB155_RS03180	657782..657874	+	93	WP_001788321.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	sak / scn	608586..659962	51376

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (30-58)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6844.44 Da
• Isoelectric Point: 9.9479

>T285693 WP_077446684.1 NZ_LN854556:652616-652792 [Staphylococcus aureus]
MDRWWLSEYKEVVPMLALLKSLERRCLMITISTMLQFGLFLIALIGLVIKFIELSNKK

Nucleotide

• Length: 177 bp

Antitoxin

Nucleotide

• Length: 142 bp

>AT285693 NZ_LN854556:c652923-652782 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTTAT

Structures

Antitoxin