285691

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) txpA-SprF1/-
Location 652616..652954 Replicon chromosome
Accession NZ_LN854556
Organism Staphylococcus aureus strain B155

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag SABB155_RS14095 Protein ID WP_077446684.1
Coordinates 652616..652792 (+) Length 59 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 652780..652954 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SABB155_RS03115 647849..651634 + 3786 WP_000582158.1 hypothetical protein -
SABB155_RS03120 651624..651776 + 153 WP_001153681.1 hypothetical protein -
SABB155_RS03125 651823..652110 + 288 WP_001040261.1 hypothetical protein -
SABB155_RS03130 652168..652464 + 297 WP_000539688.1 DUF2951 domain-containing protein -
SABB155_RS14095 652616..652792 + 177 WP_077446684.1 putative holin-like toxin Toxin
- 652780..652954 - 175 - - Antitoxin
SABB155_RS03140 653004..653258 + 255 WP_000611512.1 phage holin -
SABB155_RS03145 653270..654025 + 756 WP_000861038.1 CHAP domain-containing protein -
SABB155_RS03150 654216..654707 + 492 WP_000919350.1 staphylokinase -
SABB155_RS14605 655357..655692 + 336 Protein_606 SH3 domain-containing protein -
SABB155_RS03160 656201..656551 + 351 WP_000702262.1 complement inhibitor SCIN-A -
SABB155_RS03165 656604..656864 - 261 WP_001791826.1 hypothetical protein -
SABB155_RS03175 657175..657354 - 180 WP_000669789.1 hypothetical protein -
SABB155_RS03180 657782..657874 + 93 WP_001788321.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sak / scn 608586..659962 51376


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(30-58)


Sequences


Toxin        


Download         Length: 59 a.a.        Molecular weight: 6844.44 Da        Isoelectric Point: 9.9479

>T285691 WP_077446684.1 NZ_LN854556:652616-652792 [Staphylococcus aureus]
MDRWWLSEYKEVVPMLALLKSLERRCLMITISTMLQFGLFLIALIGLVIKFIELSNKK

Download         Length: 177 bp


Antitoxin


Download         Length: 175 bp

>AT285691 NZ_LN854556:c652954-652780 [Staphylococcus aureus]
ATTTGATATTTATATTATGGTGTGTTAATTTATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCC
GTTAAAAAGACGGTGGCTATTTTAGATTAAAGATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGAT
GGTTATTTTTTATTG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References