Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 979535..980355 Replicon chromosome
Accession NZ_LN847264
Organism Pseudomonas sp. CCOS 191

Toxin (Protein)


Gene name yhaV Uniprot ID A0A0F7Y1C6
Locus tag CCOS191_RS04520 Protein ID WP_046854219.1
Coordinates 979535..980032 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A0F7XX37
Locus tag CCOS191_RS04525 Protein ID WP_046854220.1
Coordinates 980029..980355 (-) Length 109 a.a.

Genomic Context

CCOS191_RS04500CCOS191_RS04505CCOS191_RS04510CCOS191_RS04515CCOS191_RS04535CCOS191_RS04540CCOS191_RS04545CCOS191_RS04520CCOS191_RS04525CCOS191_RS04530
Location: 974714..976240 (1527 bp)
Type: Others
Protein ID: WP_046854216.1
Location: 976237..978414 (2178 bp)
Type: Others
Protein ID: WP_046854217.1
Location: 978419..978619 (201 bp)
Type: Others
Protein ID: WP_008097766.1
Location: 978630..979490 (861 bp)
Type: Others
Protein ID: WP_046854218.1
Location: 981171..982076 (906 bp)
Type: Others
Protein ID: WP_046854222.1
Location: 982355..983896 (1542 bp)
Type: Others
Protein ID: WP_046854223.1
Location: 983924..984985 (1062 bp)
Type: Others
Protein ID: WP_046854224.1
Location: 979535..980032 (498 bp)
Type: Toxin
Protein ID: WP_046854219.1
Location: 980029..980355 (327 bp)
Type: Antitoxin
Protein ID: WP_046854220.1
Location: 980464..980910 (447 bp)
Type: Others
Protein ID: WP_046854221.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CCOS191_RS04500974714..976240+1527WP_046854216.1efflux transporter outer membrane subunit-
CCOS191_RS04505976237..978414+2178WP_046854217.1FUSC family protein-
CCOS191_RS04510978419..978619+201WP_008097766.1DUF1656 domain-containing protein-
CCOS191_RS04515978630..979490+861WP_046854218.1HlyD family secretion protein-
CCOS191_RS04520979535..980032-498WP_046854219.1type II toxin-antitoxin system YhaV family toxinToxin
CCOS191_RS04525980029..980355-327WP_046854220.1type II toxin-antitoxin system PrlF family antitoxinAntitoxin
CCOS191_RS04530980464..980910-447WP_046854221.1universal stress protein-
CCOS191_RS04535981171..982076+906WP_046854222.1LysR family transcriptional regulator-
CCOS191_RS04540982355..983896+1542WP_046854223.1MFS transporter-
CCOS191_RS04545983924..984985+1062WP_046854224.1HlyD family secretion protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-106)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 19122.90 Da        Isoelectric Point: 10.4165

>T285682 WP_046854219.1 NZ_LN847264:c980032-979535 [Pseudomonas sp. CCOS 191]
MTETRRKPLCVHGWSVFAHPLFLDKLEALIDEVEVLQRKDPVGYVKKNAAKRLKAIRRLAFDVIAQAPGNPDHRMGGTLG
AEHKHWFRAKFFQQYRLFFRYHASSKIIVLAWVNDDNSKRAYESSDDAYRVFRRMLGNGHPPDDWDQLLQEAAAATARFN
ATLKR

Download         Length: 498 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12069.53 Da        Isoelectric Point: 4.2140

>AT285682 WP_046854220.1 NZ_LN847264:c980355-980029 [Pseudomonas sp. CCOS 191]
MATTFEAESTLTERYQTTVPETVRRALGLKKRDKIHYSIRPDGAVILTRAETAEEDPAVGQFLEFLERDIATNPQRLKVV
DAELVARLDALVGDVEIDLDQPLSADDE

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A0F7Y1C6

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A0F7XX37

References