Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | DinJ-YafQ (relBE)/YafQ-RelB |
Location | 246129..246670 | Replicon | chromosome |
Accession | NZ_LN832404 | ||
Organism | Escherichia coli K-12 substr. AG100 |
Toxin (Protein)
Gene name | yafQ | Uniprot ID | Q47149 |
Locus tag | EK12AG100_RS01150 | Protein ID | WP_000615983.1 |
Coordinates | 246129..246407 (-) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | dinJ | Uniprot ID | Q47150 |
Locus tag | EK12AG100_RS01155 | Protein ID | WP_000729703.1 |
Coordinates | 246410..246670 (-) | Length | 87 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EK12AG100_RS01135 | 243711..244289 | + | 579 | WP_000284050.1 | D-sedoheptulose 7-phosphate isomerase | - |
EK12AG100_RS01140 | 244495..245262 | + | 768 | WP_000333380.1 | class II glutamine amidotransferase | - |
EK12AG100_RS01145 | 245233..245973 | - | 741 | WP_001225679.1 | murein L,D-transpeptidase | - |
EK12AG100_RS01150 | 246129..246407 | - | 279 | WP_000615983.1 | type II toxin-antitoxin system mRNA interferase toxin YafQ | Toxin |
EK12AG100_RS01155 | 246410..246670 | - | 261 | WP_000729703.1 | type II toxin-antitoxin system antitoxin DinJ | Antitoxin |
EK12AG100_RS01160 | 246880..247629 | + | 750 | WP_000056849.1 | C40 family peptidase | - |
EK12AG100_RS01165 | 247805..248302 | + | 498 | WP_000006255.1 | REP-associated tyrosine transposase RayT | - |
EK12AG100_RS01170 | 248526..250238 | - | 1713 | Protein_225 | flagellar biosynthesis protein FlhA | - |
EK12AG100_RS01175 | 250210..250995 | + | 786 | WP_000207552.1 | putative lateral flagellar export/assembly protein LafU | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
PDB | 4Q2U |
Antitoxin
Source | ID | Structure |
---|---|---|
PDB | 4Q2U | |
AlphaFold DB | A0A5F1F716 |