285633

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2484879..2485063 Replicon chromosome
Accession NZ_LN831036
Organism Staphylococcus aureus strain NCTC13435

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag AT694_RS12660 Protein ID WP_000482652.1
Coordinates 2484956..2485063 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2484879..2484939 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AT694_RS12635 2480334..2480501 - 168 WP_001790576.1 hypothetical protein -
AT694_RS12645 2480732..2482465 - 1734 WP_000486495.1 ABC transporter ATP-binding protein/permease -
AT694_RS12650 2482490..2484253 - 1764 WP_001064837.1 ABC transporter ATP-binding protein/permease -
- 2484879..2484939 + 61 - - Antitoxin
AT694_RS12660 2484956..2485063 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
AT694_RS12665 2485197..2485583 - 387 WP_000779357.1 flippase GtxA -
AT694_RS12670 2485851..2486993 + 1143 WP_001176863.1 glycerate kinase -
AT694_RS12675 2487053..2487712 + 660 WP_000831298.1 membrane protein -
AT694_RS12680 2487894..2489105 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
AT694_RS12685 2489228..2489701 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T285633 WP_000482652.1 NZ_LN831036:c2485063-2484956 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT285633 NZ_LN831036:2484879-2484939 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References