285631

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2200302..2200519 Replicon chromosome
Accession NZ_LN831036
Organism Staphylococcus aureus strain NCTC13435

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag AT694_RS11165 Protein ID WP_001802298.1
Coordinates 2200415..2200519 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2200302..2200357 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AT694_RS11145 2196439..2197104 - 666 WP_001024094.1 SDR family oxidoreductase -
AT694_RS11150 2197256..2197576 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
AT694_RS11155 2197578..2198558 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
AT694_RS11160 2198824..2199915 + 1092 WP_000495670.1 lytic regulatory protein -
- 2200302..2200357 + 56 - - Antitoxin
AT694_RS11165 2200415..2200519 - 105 WP_001802298.1 hypothetical protein Toxin
AT694_RS14735 2201199..2201357 + 159 WP_001792784.1 hypothetical protein -
AT694_RS11170 2202015..2202872 - 858 WP_000370929.1 Cof-type HAD-IIB family hydrolase -
AT694_RS11175 2202940..2203722 - 783 WP_000908179.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T285631 WP_001802298.1 NZ_LN831036:c2200519-2200415 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 56 bp

>AT285631 NZ_LN831036:2200302-2200357 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References