Detailed information of TA system TA285523

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2087897..2088143
• Replicon: chromosome
• Accession: NZ_LN680001
• Organism: Bacillus subtilis strain BS34A

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: VV28_RS22755
• Protein ID: WP_109789044.1
• Coordinates: 2087897..2087989 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2087970..2088143 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
VV28_RS10055	2083056..2083391	+	336	WP_009967409.1	hypothetical protein	-
VV28_RS10060	2083438..2087043	-	3606	WP_004399367.1	membrane protein	-
VV28_RS10065	2087276..2087608	-	333	WP_026009814.1	hypothetical protein	-
VV28_RS22755	2087897..2087989	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2087970..2088143	-	174	-	-	Antitoxin
VV28_RS10070	2088258..2089100	-	843	WP_003231327.1	hypothetical protein	-
VV28_RS10075	2089300..2089758	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
VV28_RS10080	2089768..2091570	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
VV28_RS10085	2091672..2092229	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2073882..2097560	23678
	-	inside	Prophage	-	-	2073882..2096640	22758

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T285523 WP_109789044.1 NZ_LN680001:2087897-2087989 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

Antitoxin

Nucleotide

• Length: 174 bp

>AT285523 NZ_LN680001:c2088143-2087970 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin