Detailed information of TA system TA285502

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 2087895..2088141
• Replicon: chromosome
• Accession: NZ_LN649259
• Organism: Bacillus subtilis strain BS49

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: VV34_RS23985
• Protein ID: WP_109789044.1
• Coordinates: 2087895..2087987 (+)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2087968..2088141 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
VV34_RS10525	2083054..2083389	+	336	WP_009967409.1	hypothetical protein	-
VV34_RS10530	2083436..2087041	-	3606	WP_004399367.1	membrane protein	-
VV34_RS10535	2087274..2087606	-	333	WP_026009814.1	hypothetical protein	-
VV34_RS23985	2087895..2087987	+	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
-	2087968..2088141	-	174	-	-	Antitoxin
VV34_RS10540	2088256..2089098	-	843	WP_003231327.1	hypothetical protein	-
VV34_RS10545	2089298..2089756	-	459	WP_003231326.1	type II toxin-antitoxin system antitoxin YobK	-
VV34_RS10550	2089766..2091568	-	1803	WP_004399481.1	type II toxin-antitoxin system toxin ribonuclease YobL	-
VV34_RS10555	2091670..2092227	-	558	WP_004399321.1	SMI1/KNR4 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2073880..2097558	23678

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T285502 WP_109789044.1 NZ_LN649259:2087895-2087987 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

Antitoxin

Nucleotide

• Length: 174 bp

>AT285502 NZ_LN649259:c2088141-2087968 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin