Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2560303..2560487 Replicon chromosome
Accession NZ_LN626917
Organism Staphylococcus aureus strain ILRI_Eymole1/1 isolate Staphylococcus aureus isolate ILRI_Eymole1/1

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SRS_RS13200 Protein ID WP_000482647.1
Coordinates 2560380..2560487 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2560303..2560363 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SRS_RS13175 2555813..2555980 - 168 Protein_2502 hypothetical protein -
SRS_RS13185 2556211..2557944 - 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
SRS_RS13190 2557969..2559732 - 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
- 2560303..2560363 + 61 - - Antitoxin
SRS_RS13200 2560380..2560487 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SRS_RS13205 2560621..2561007 - 387 WP_000779351.1 flippase GtxA -
SRS_RS13210 2561275..2562417 + 1143 WP_001176855.1 glycerate kinase -
SRS_RS13215 2562477..2563136 + 660 WP_000831298.1 membrane protein -
SRS_RS13220 2563318..2564529 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
SRS_RS13225 2564652..2565125 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T285498 WP_000482647.1 NZ_LN626917:c2560487-2560380 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT285498 NZ_LN626917:2560303-2560363 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References