Detailed information of TA system TA285493

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1905438..1905618
• Replicon: chromosome
• Accession: NZ_LN626917
• Organism: Staphylococcus aureus strain ILRI_Eymole1/1 isolate Staphylococcus aureus isolate ILRI_Eymole1/1

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SRS_RS15600
• Protein ID: WP_001801861.1
• Coordinates: 1905438..1905533 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1905561..1905618 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SRS_RS09530	1900582..1901208	+	627	WP_000669038.1	hypothetical protein	-
SRS_RS09535	1901249..1901593	+	345	WP_000627550.1	DUF3969 family protein	-
SRS_RS09540	1901691..1902263	+	573	WP_000414222.1	hypothetical protein	-
SRS_RS09545	1902412..1903779	-	1368	WP_001093574.1	FRG domain-containing protein	-
SRS_RS09550	1903779..1904348	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
SRS_RS09555	1904541..1904987	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
SRS_RS15600	1905438..1905533	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1905561..1905618	-	58	-	-	Antitoxin
SRS_RS09560	1905656..1905757	+	102	WP_001791232.1	hypothetical protein	-
SRS_RS15210	1905932..1906374	-	443	Protein_1862	DUF1433 domain-containing protein	-
SRS_RS09570	1906374..1906817	-	444	WP_000731421.1	DUF1433 domain-containing protein	-
SRS_RS15215	1906817..1907259	-	443	Protein_1864	DUF1433 domain-containing protein	-
SRS_RS09580	1907785..1910205	+	2421	WP_045179297.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T285493 WP_001801861.1 NZ_LN626917:1905438-1905533 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

Antitoxin

Nucleotide

• Length: 58 bp

>AT285493 NZ_LN626917:c1905618-1905561 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin