Detailed information of TA system TA285489

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1459317..1459514
• Replicon: chromosome
• Accession: NZ_LN626917
• Organism: Staphylococcus aureus strain ILRI_Eymole1/1 isolate Staphylococcus aureus isolate ILRI_Eymole1/1

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: SRS_RS07240
• Protein ID: WP_000623369.1
• Coordinates: 1459407..1459514 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	1459317..1459354 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SRS_RS07210	1454510..1454797	-	288	WP_000410718.1	hypothetical protein	-
SRS_RS15100	1455138..1455428	+	291	WP_001791476.1	hypothetical protein	-
SRS_RS07220	1455516..1456157	-	642	WP_000571183.1	ABC transporter ATP-binding protein	-
SRS_RS07225	1456154..1456474	-	321	WP_000873929.1	YxeA family protein	-
SRS_RS07230	1456477..1458441	-	1965	WP_045179017.1	bacteriocin-associated integral membrane family protein	-
SRS_RS15105	1458485..1458757	-	273	WP_001794574.1	lactococcin 972 family bacteriocin	-
SRS_RS07235	1458767..1458868	-	102	WP_001790623.1	hypothetical protein	-
-	1459317..1459354	+	38	-	-	Antitoxin
SRS_RS07240	1459407..1459514	-	108	WP_000623369.1	putative holin-like toxin	Toxin
SRS_RS07245	1459785..1460387	-	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
SRS_RS07250	1460402..1460578	-	177	WP_000214898.1	YkvS family protein	-
SRS_RS07255	1460777..1461763	+	987	WP_000668820.1	lipoate--protein ligase	-
SRS_RS07260	1461844..1462062	-	219	WP_045179020.1	IDEAL domain-containing protein	-
SRS_RS07265	1462272..1462841	+	570	WP_000287265.1	competence protein ComK	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T285489 WP_000623369.1 NZ_LN626917:c1459514-1459407 [Staphylococcus aureus]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 38 bp

>AT285489 NZ_LN626917:1459317-1459354 [Staphylococcus aureus]
AACATGTCGCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Antitoxin