Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 1703604..1704208 Replicon chromosome
Accession NZ_LN614827
Organism Legionella fallonii LLAP-10

Toxin (Protein)


Gene name higB Uniprot ID A0A098G3A3
Locus tag LFA_RS06905 Protein ID WP_045095532.1
Coordinates 1703897..1704208 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LFA_RS06900 Protein ID WP_045095531.1
Coordinates 1703604..1703894 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LFA_RS06880 1700695..1701318 + 624 WP_045095527.1 recombinase family protein -
LFA_RS06885 1701429..1702448 + 1020 WP_045095528.1 hypothetical protein -
LFA_RS06890 1702815..1703171 - 357 WP_045095529.1 hypothetical protein -
LFA_RS06895 1703172..1703567 - 396 WP_045095530.1 hypothetical protein -
LFA_RS06900 1703604..1703894 - 291 WP_045095531.1 helix-turn-helix domain-containing protein Antitoxin
LFA_RS06905 1703897..1704208 - 312 WP_045095532.1 hypothetical protein Toxin
LFA_RS06910 1704771..1705757 + 987 WP_045095533.1 FRG domain-containing protein -
LFA_RS06915 1705997..1706833 - 837 WP_045095534.1 hypothetical protein -
LFA_RS06920 1706949..1707920 - 972 WP_197541205.1 DUF3644 domain-containing protein -
LFA_RS06925 1708005..1708553 - 549 WP_045095536.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(37-88)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11996.85 Da        Isoelectric Point: 9.2614

>T285482 WP_045095532.1 NZ_LN614827:c1704208-1703897 [Legionella fallonii LLAP-10]
MIFIETPIFTEDVKELLLDEEYAEFQKYLADNPLAGDVIQQTGGLRKVRWSSQGKGKRGGVRVIYYYVTPASQIRLLLIY
KKGIQDDLSADQKKMLRQLNERW

Download         Length: 312 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11042.76 Da        Isoelectric Point: 8.0670

>AT285482 WP_045095531.1 NZ_LN614827:c1703894-1703604 [Legionella fallonii LLAP-10]
MDKKLFERLYESMTQMNEIIDGERVPSREFLVDAVHVKEIRKKTGLTQEKFCHLIDVNIGTLRNWEQGRREPTGPAKALL
RAINKDPEHVLAALAS

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A098G3A3

Antitoxin

Source ID Structure

References