Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3643282..3643504 Replicon chromosome
Accession NZ_LM995446
Organism Escherichia coli strain K-12 substr. RV308

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag ECRV308_RS18065 Protein ID WP_000141634.1
Coordinates 3643282..3643389 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3643438..3643504 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECRV308_RS18040 3638535..3639287 - 753 Protein_3435 cellulose biosynthesis protein BcsQ -
ECRV308_RS18045 3639299..3639487 - 189 WP_001063318.1 YhjR family protein -
ECRV308_RS18050 3639760..3641331 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
ECRV308_RS18055 3641328..3641519 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
ECRV308_RS18060 3641516..3643195 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
ECRV308_RS18065 3643282..3643389 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3643438..3643504 + 67 - - Antitoxin
ECRV308_RS18075 3643865..3645136 + 1272 WP_001295225.1 transporter -
ECRV308_RS18080 3645166..3646170 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
ECRV308_RS18085 3646167..3647150 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
ECRV308_RS18090 3647161..3648063 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T285449 WP_000141634.1 NZ_LM995446:c3643389-3643282 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

Antitoxin


Download         Length: 67 bp

>AT285449 NZ_LM995446:3643438-3643504 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References