Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5144349..5144938 Replicon chromosome
Accession NZ_HG992342
Organism Xanthomonas arboricola pv. corylina strain CFBP 6600 isolate K100-1

Toxin (Protein)


Gene name graT Uniprot ID A0A2N7V9W3
Locus tag P3C55_RS22135 Protein ID WP_016902142.1
Coordinates 5144657..5144938 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag P3C55_RS22130 Protein ID WP_026064232.1
Coordinates 5144349..5144639 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P3C55_RS22100 5140474..5141055 + 582 WP_275544325.1 ParA family protein -
P3C55_RS22105 (CFBP6600_44090) 5141069..5142031 - 963 WP_070689987.1 IS1595 family transposase -
P3C55_RS22110 5142142..5142654 + 513 WP_275544326.1 hypothetical protein -
P3C55_RS22115 (CFBP6600_44100) 5142669..5143316 + 648 WP_104536557.1 RelA/SpoT domain-containing protein -
P3C55_RS22120 (CFBP6600_44110) 5143474..5143806 + 333 WP_026064233.1 hypothetical protein -
P3C55_RS22125 5143956..5144158 + 203 Protein_4328 hypothetical protein -
P3C55_RS22130 (CFBP6600_44130) 5144349..5144639 - 291 WP_026064232.1 HigA family addiction module antitoxin Antitoxin
P3C55_RS22135 (CFBP6600_44140) 5144657..5144938 - 282 WP_016902142.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P3C55_RS22140 (CFBP6600_44150) 5145078..5147204 - 2127 WP_104613293.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-67)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11064.75 Da        Isoelectric Point: 9.7972

>T285268 WP_016902142.1 NZ_HG992342:c5144938-5144657 [Xanthomonas arboricola pv. corylina]
MIRSFVDKEAEKIWMGERSRRLPADIQSVARRKLRMLNAAAHLDDLRIPPANRLEALKGERRGQYSIRINDQWRICFRWM
EGDVAEVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10555.21 Da        Isoelectric Point: 8.7586

>AT285268 WP_026064232.1 NZ_HG992342:c5144639-5144349 [Xanthomonas arboricola pv. corylina]
MTVLPNIHPGEILREEFLEPMGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTTERFWLSLQADYELEQA
HRALGDLPSRIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N7V9W3

Antitoxin

Source ID Structure

References