Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5014980..5015569 Replicon chromosome
Accession NZ_HG992341
Organism Xanthomonas arboricola pv. corylina strain CFBP 1159

Toxin (Protein)


Gene name graT Uniprot ID A0A2N7V9W3
Locus tag P3C48_RS21320 Protein ID WP_016902142.1
Coordinates 5015288..5015569 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag P3C48_RS21315 Protein ID WP_026064232.1
Coordinates 5014980..5015270 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P3C48_RS21290 (CFBP1159_42260) 5010611..5011432 + 822 WP_026064234.1 restriction endonuclease -
P3C48_RS21295 (CFBP1159_42270) 5011771..5012622 + 852 WP_146091500.1 hypothetical protein -
P3C48_RS21300 5013411..5013935 - 525 WP_104613292.1 hypothetical protein -
P3C48_RS21305 (CFBP1159_42280) 5014105..5014437 + 333 WP_026064233.1 hypothetical protein -
P3C48_RS21310 5014587..5014789 + 203 Protein_4166 hypothetical protein -
P3C48_RS21315 (CFBP1159_42300) 5014980..5015270 - 291 WP_026064232.1 HigA family addiction module antitoxin Antitoxin
P3C48_RS21320 (CFBP1159_42310) 5015288..5015569 - 282 WP_016902142.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P3C48_RS21325 (CFBP1159_42320) 5015709..5017835 - 2127 WP_275548228.1 exodeoxyribonuclease V subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-67)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11064.75 Da        Isoelectric Point: 9.7972

>T285265 WP_016902142.1 NZ_HG992341:c5015569-5015288 [Xanthomonas arboricola pv. corylina]
MIRSFVDKEAEKIWMGERSRRLPADIQSVARRKLRMLNAAAHLDDLRIPPANRLEALKGERRGQYSIRINDQWRICFRWM
EGDVAEVEIVDYH

Download         Length: 282 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10555.21 Da        Isoelectric Point: 8.7586

>AT285265 WP_026064232.1 NZ_HG992341:c5015270-5014980 [Xanthomonas arboricola pv. corylina]
MTVLPNIHPGEILREEFLEPMGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTTERFWLSLQADYELEQA
HRALGDLPSRIKRLAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2N7V9W3

Antitoxin

Source ID Structure

References