Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 434216..434747 Replicon chromosome
Accession NZ_HG969192
Organism Bartonella tribocorum strain BM1374166

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag BM1374166_RS01780 Protein ID WP_038473264.1
Coordinates 434216..434488 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID A9INW3
Locus tag BM1374166_RS01785 Protein ID WP_012230893.1
Coordinates 434490..434747 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BM1374166_RS01770 430048..430602 + 555 WP_012230889.1 biotin transporter BioY -
BM1374166_RS01775 431024..431332 + 309 WP_038473261.1 hypothetical protein -
BM1374166_RS01780 434216..434488 - 273 WP_038473264.1 type II toxin-antitoxin system YafQ family toxin Toxin
BM1374166_RS01785 434490..434747 - 258 WP_012230893.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BM1374166_RS01790 435035..435648 - 614 Protein_339 hypothetical protein -
BM1374166_RS01800 436095..437858 + 1764 WP_012230898.1 ShlB/FhaC/HecB family hemolysin secretion/activation protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10767.62 Da        Isoelectric Point: 10.2928

>T285245 WP_038473264.1 NZ_HG969192:c434488-434216 [Bartonella tribocorum]
MLIPVRSRQFKRDVRKAEKRGKNMNKLRTLLSLLIEEKPLPRHYCDHPLKGDWVGYHDIHIEPDWLLIYRIEGGKLHLIR
TGTHSDLFKE

Download         Length: 273 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9467.19 Da        Isoelectric Point: 10.1958

>AT285245 WP_012230893.1 NZ_HG969192:c434747-434490 [Bartonella tribocorum]
MKTDSVVRARIPAEMKKQAMITLERMGLSASDLIRITFLRVAEEGCLPFDLKVPNSVTRKAIKELDEGKGKTFKNADALF
KDLGI

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A9INW3

References