285146

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2713644..2714215 Replicon chromosome
Accession NZ_HG938353
Organism Neorhizobium galegae bv. orientalis str. HAMBI 540

Toxin (Protein)


Gene name yoeB Uniprot ID A0A068SSS8
Locus tag RG540_RS13430 Protein ID WP_038588722.1
Coordinates 2713644..2713928 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A068SV24
Locus tag RG540_RS13435 Protein ID WP_038588724.1
Coordinates 2713928..2714215 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG540_RS13410 2709570..2710625 - 1056 Protein_2678 NAD(P)-binding domain-containing protein -
RG540_RS13415 2710761..2711231 + 471 WP_038588716.1 pyridoxamine 5'-phosphate oxidase family protein -
RG540_RS13420 2711237..2712571 + 1335 WP_038593763.1 GAF domain-containing protein -
RG540_RS13425 2712829..2713572 - 744 WP_038588719.1 hypothetical protein -
RG540_RS13430 2713644..2713928 - 285 WP_038588722.1 Txe/YoeB family addiction module toxin Toxin
RG540_RS13435 2713928..2714215 - 288 WP_038588724.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
RG540_RS13440 2714276..2715025 - 750 WP_038588726.1 metallophosphatase family protein -
RG540_RS13445 2715025..2715381 - 357 WP_038588728.1 hydroxyisourate hydrolase -
RG540_RS13450 2715378..2715878 - 501 WP_038593765.1 ureidoglycolate lyase -
RG540_RS13455 2715893..2716255 - 363 WP_038588729.1 DUF86 domain-containing protein -
RG540_RS13460 2716252..2716542 - 291 WP_038588732.1 nucleotidyltransferase family protein -
RG540_RS13465 2716611..2717108 - 498 WP_038588735.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase -
RG540_RS13470 2717105..2718031 - 927 WP_038588738.1 allantoinase PuuE -
RG540_RS13475 2718104..2718406 - 303 WP_038588741.1 AzlD domain-containing protein -
RG540_RS13480 2718403..2719071 - 669 WP_046600994.1 AzlC family ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(11-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11474.20 Da        Isoelectric Point: 9.5449

>T285146 WP_038588722.1 NZ_HG938353:c2713928-2713644 [Neorhizobium galegae bv. orientalis str. HAMBI 540]
MPSGKAYLLVWEPEGWREYIFWQETDPKMVVRINELIRDTLRHPFEGIGKPEPLRNQLKGQWSRRITQEHRLVYRVENGN
DQPRLIILQCRFHY

Download         Length: 285 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10737.25 Da        Isoelectric Point: 4.4335

>AT285146 WP_038588724.1 NZ_HG938353:c2714215-2713928 [Neorhizobium galegae bv. orientalis str. HAMBI 540]
MRTVMFSQARQELASLLDEVSNDRAPIEIMRRDKPSAILIDKDEYEGMLETLHLMSTPANATRLIEAIANVNDGSKLIVH
DLIEPEDYIPNKKAD

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A068SSS8

Antitoxin

Source ID Structure
AlphaFold DB A0A068SV24

References