285139

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 497762..498354 Replicon chromosome
Accession NZ_HG938353
Organism Neorhizobium galegae bv. orientalis str. HAMBI 540

Toxin (Protein)


Gene name graT Uniprot ID A0A068SLQ8
Locus tag RG540_RS02375 Protein ID WP_038584166.1
Coordinates 497762..498046 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag RG540_RS02380 Protein ID WP_038584168.1
Coordinates 498058..498354 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RG540_RS02360 493833..494384 + 552 WP_038540412.1 LemA family protein -
RG540_RS02365 494472..495746 + 1275 WP_157884641.1 3-phosphoshikimate 1-carboxyvinyltransferase -
RG540_RS02370 495792..497720 + 1929 WP_038584165.1 DUF2207 domain-containing protein -
RG540_RS02375 497762..498046 + 285 WP_038584166.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RG540_RS02380 498058..498354 + 297 WP_038584168.1 HigA family addiction module antidote protein Antitoxin
RG540_RS02385 498446..500662 + 2217 WP_038584169.1 glycine--tRNA ligase subunit beta -
RG540_RS02390 500744..502597 - 1854 WP_038584170.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(14-94)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(6-79)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10517.00 Da        Isoelectric Point: 8.0882

>T285139 WP_038584166.1 NZ_HG938353:497762-498046 [Neorhizobium galegae bv. orientalis str. HAMBI 540]
MAIRSYADAMTQSIASGKVPKGFPADLARRAVRKLTMIENAMELHDLRSPPGNHLEALKGDRAGQHSIRVNDQWRICFVW
TTAGAEQVEIVDYH

Download         Length: 285 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10924.62 Da        Isoelectric Point: 6.7257

>AT285139 WP_038584168.1 NZ_HG938353:498058-498354 [Neorhizobium galegae bv. orientalis str. HAMBI 540]
MASLLPPVHPGEILREEYLAPLHLSAGALAKKLNVPRTRIERLVAEQTSVTTDTALRLGRFFDTTPEFWMNLQTSYDLKV
ESTAKREEIAAIPVIHAA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A068SLQ8

Antitoxin

Source ID Structure

References