Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3081071..3081293 Replicon chromosome
Accession NZ_HG738867
Organism Escherichia coli str. K-12 substr. MC4100 strain K-12

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag BN896_RS22490 Protein ID WP_000141634.1
Coordinates 3081186..3081293 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3081071..3081137 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BN896_RS15210 (BN896_3231) 3076512..3077414 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
BN896_RS15215 (BN896_3230) 3077425..3078408 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
BN896_RS15220 (BN896_3229) 3078405..3079409 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
BN896_RS15225 (BN896_3228) 3079439..3080710 - 1272 WP_001295225.1 transporter -
- 3081071..3081137 - 67 - - Antitoxin
BN896_RS22490 (BN896_3227) 3081186..3081293 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
BN896_RS15240 (BN896_3226) 3081380..3083059 - 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
BN896_RS15245 (BN896_3225) 3083056..3083247 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
BN896_RS15250 (BN896_3224) 3083244..3084815 - 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
BN896_RS15255 (BN896_3223) 3085088..3085276 + 189 WP_001063318.1 YhjR family protein -
BN896_RS15260 3085288..3086040 + 753 Protein_2893 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T285024 WP_000141634.1 NZ_HG738867:3081186-3081293 [Escherichia coli str. K-12 substr. MC4100]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T285024 NZ_HG738867:3081186-3081293 [Escherichia coli str. K-12 substr. MC4100]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT285024 NZ_HG738867:c3081137-3081071 [Escherichia coli str. K-12 substr. MC4100]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References