Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) bsrG-as-bsrG/-
Location 1863422..1863719 Replicon chromosome
Accession NZ_CP128551
Organism Bacillus velezensis strain SRCM123441

Toxin (Protein)


Gene name bsrG Uniprot ID L8EAY0
Locus tag QTN52_RS09105 Protein ID WP_009967548.1
Coordinates 1863603..1863719 (-) Length 39 a.a.

Antitoxin (RNA)


Gene name as-bsrG
Locus tag -
Coordinates 1863422..1863608 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTN52_RS09080 (1858730) 1858730..1859713 - 984 WP_182077776.1 thermonuclease family protein -
QTN52_RS09085 (1859885) 1859885..1861600 + 1716 WP_182077777.1 T7SS effector LXG polymorphic toxin -
QTN52_RS09090 (1861609) 1861609..1862106 + 498 WP_019712870.1 SMI1/KNR4 family protein -
QTN52_RS09095 (1862170) 1862170..1862748 + 579 WP_182077778.1 SMI1/KNR4 family protein -
QTN52_RS09100 (1862784) 1862784..1863317 + 534 WP_019712872.1 GNAT family protein -
- (1863422) 1863422..1863608 + 187 NuclAT_0 - Antitoxin
- (1863422) 1863422..1863608 + 187 NuclAT_0 - Antitoxin
- (1863422) 1863422..1863608 + 187 NuclAT_0 - Antitoxin
- (1863422) 1863422..1863608 + 187 NuclAT_0 - Antitoxin
QTN52_RS09105 (1863603) 1863603..1863719 - 117 WP_009967548.1 type I toxin-antitoxin system toxin BsrG Toxin
QTN52_RS09110 (1863959) 1863959..1864162 + 204 WP_021493638.1 hypothetical protein -
QTN52_RS09115 (1864291) 1864291..1865064 + 774 WP_104842635.1 sporulation protein YunB -
QTN52_RS09120 (1865292) 1865292..1865624 + 333 WP_014472056.1 YolD-like family protein -
QTN52_RS09125 (1865617) 1865617..1866867 + 1251 WP_062623501.1 UV damage repair protein UvrX -
QTN52_RS09130 (1867031) 1867031..1868191 - 1161 WP_181816507.1 tetratricopeptide repeat protein -
QTN52_RS09135 (1868343) 1868343..1868621 - 279 WP_022553060.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1840369..1996547 156178


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-38)


Sequences


Toxin        


Download         Length: 39 a.a.        Molecular weight: 4336.39 Da        Isoelectric Point: 10.1022

>T284879 WP_009967548.1 NZ_CP128551:c1863719-1863603 [Bacillus velezensis]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Download         Length: 117 bp


Antitoxin


Download         Length: 187 bp

>AT284879 NZ_CP128551:1863422-1863608 [Bacillus velezensis]
AATGATACAAATAATTATTTATTGCATTTTGATTTGTGGAAATGCATAAAATAAAAAAAGACCTGGGGTGCGCTAACACC
CACTGGTCATTGTTTGTACAAAAAGCTGCCCATCAAAGGGCTTGCTCGTTGTCAAATCTGCGTAGGCCTAACCCTTCAGG
TGTCCAAACTCAAGGGAAGGTCTATTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7Z7EVU9


Antitoxin

Download structure file

References