Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1972848..1973548 Replicon chromosome
Accession NZ_CP128550
Organism Pseudomonas alloputida strain NMI5594_09

Toxin (Protein)


Gene name mqsR Uniprot ID Q88F93
Locus tag LU693_RS09010 Protein ID WP_010954960.1
Coordinates 1972848..1973144 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID I7AUJ7
Locus tag LU693_RS09015 Protein ID WP_003254235.1
Coordinates 1973147..1973548 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU693_RS08990 (LU693_008990) 1968840..1970018 - 1179 WP_010954964.1 efflux RND transporter periplasmic adaptor subunit -
LU693_RS08995 (LU693_008995) 1970231..1970707 + 477 WP_010954963.1 sigma-70 family RNA polymerase sigma factor -
LU693_RS09000 (LU693_009000) 1970876..1971355 + 480 WP_010954962.1 hypothetical protein -
LU693_RS09005 (LU693_009005) 1971428..1972753 + 1326 WP_010954961.1 MFS transporter -
LU693_RS09010 (LU693_009010) 1972848..1973144 + 297 WP_010954960.1 type II toxin-antitoxin system MqsR family toxin Toxin
LU693_RS09015 (LU693_009015) 1973147..1973548 + 402 WP_003254235.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
LU693_RS09020 (LU693_009020) 1973620..1975302 - 1683 WP_010954959.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
LU693_RS09025 (LU693_009025) 1975838..1976587 + 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -
LU693_RS09030 (LU693_009030) 1976588..1977517 + 930 WP_010954958.1 FAD-binding protein -
LU693_RS09035 (LU693_009035) 1977593..1978414 + 822 WP_010954957.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11133.22 Da        Isoelectric Point: 10.2271

>T284872 WP_010954960.1 NZ_CP128550:1972848-1973144 [Pseudomonas alloputida]
MEKRMPHCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14684.76 Da        Isoelectric Point: 4.9531

>AT284872 WP_003254235.1 NZ_CP128550:1973147-1973548 [Pseudomonas alloputida]
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q88F93

Antitoxin

Source ID Structure
AlphaFold DB I7AUJ7

References