Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1981537..1982237 Replicon chromosome
Accession NZ_CP128540
Organism Pseudomonas alloputida strain NMI24_14

Toxin (Protein)


Gene name mqsR Uniprot ID Q88F93
Locus tag LU682_RS09080 Protein ID WP_010954960.1
Coordinates 1981537..1981833 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID I7AUJ7
Locus tag LU682_RS09085 Protein ID WP_003254235.1
Coordinates 1981836..1982237 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LU682_RS09060 (LU682_009060) 1977529..1978707 - 1179 WP_010954964.1 efflux RND transporter periplasmic adaptor subunit -
LU682_RS09065 (LU682_009065) 1978920..1979396 + 477 WP_010954963.1 sigma-70 family RNA polymerase sigma factor -
LU682_RS09070 (LU682_009070) 1979565..1980044 + 480 WP_010954962.1 hypothetical protein -
LU682_RS09075 (LU682_009075) 1980117..1981442 + 1326 WP_010954961.1 MFS transporter -
LU682_RS09080 (LU682_009080) 1981537..1981833 + 297 WP_010954960.1 type II toxin-antitoxin system MqsR family toxin Toxin
LU682_RS09085 (LU682_009085) 1981836..1982237 + 402 WP_003254235.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
LU682_RS09090 (LU682_009090) 1982309..1983991 - 1683 WP_010954959.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
LU682_RS09095 (LU682_009095) 1984527..1985276 + 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -
LU682_RS09100 (LU682_009100) 1985277..1986206 + 930 WP_010954958.1 FAD-binding protein -
LU682_RS09105 (LU682_009105) 1986282..1987103 + 822 WP_010954957.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11133.22 Da        Isoelectric Point: 10.2271

>T284833 WP_010954960.1 NZ_CP128540:1981537-1981833 [Pseudomonas alloputida]
MEKRMPHCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14684.76 Da        Isoelectric Point: 4.9531

>AT284833 WP_003254235.1 NZ_CP128540:1981836-1982237 [Pseudomonas alloputida]
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q88F93

Antitoxin

Source ID Structure
AlphaFold DB I7AUJ7

References