Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-Phd
Location 2539135..2539631 Replicon chromosome
Accession NC_019427
Organism Anabaena sp. 90

Toxin (Protein)


Gene name yoeB Uniprot ID K7W1R6
Locus tag ANA_RS11070 Protein ID WP_015080149.1
Coordinates 2539368..2539631 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID K7WWK3
Locus tag ANA_RS11065 Protein ID WP_015080148.1
Coordinates 2539135..2539371 (+) Length 79 a.a.

Genomic Context

ANA_RS11045ANA_RS11060ANA_RS24545ANA_RS11065ANA_RS11070ANA_RS26545ANA_RS25900ANA_RS11075ANA_RS11080ANA_RS11085ANA_RS11095ANA_RS11050ANA_RS11055ANA_RS11090ANA_RS11105
Location: 2534994..2536775 (1782 bp)
Type: Others
Protein ID: WP_015080144.1
Location: 2538462..2538689 (228 bp)
Type: Others
Protein ID: WP_015080147.1
Location: 2538690..2538785 (96 bp)
Type: Others
Protein ID: Protein_2295
Location: 2539135..2539371 (237 bp)
Type: Antitoxin
Protein ID: WP_015080148.1
Location: 2539368..2539631 (264 bp)
Type: Toxin
Protein ID: WP_015080149.1
Location: 2539624..2539776 (153 bp)
Type: Others
Protein ID: WP_015080150.1
Location: 2539764..2539901 (138 bp)
Type: Others
Protein ID: WP_174782923.1
Location: 2539981..2541075 (1095 bp)
Type: Others
Protein ID: WP_015080151.1
Location: 2541414..2542088 (675 bp)
Type: Others
Protein ID: WP_015080152.1
Location: 2542192..2542494 (303 bp)
Type: Others
Protein ID: WP_015080153.1
Location: 2543002..2543577 (576 bp)
Type: Others
Protein ID: WP_015080155.1
Location: 2537082..2537483 (402 bp)
Type: Others
Protein ID: WP_015080145.1
Location: 2537606..2537893 (288 bp)
Type: Others
Protein ID: WP_015080146.1
Location: 2542614..2542943 (330 bp)
Type: Others
Protein ID: WP_015080154.1
Location: 2543813..2544475 (663 bp)
Type: Others
Protein ID: WP_015080157.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
ANA_RS110452534994..2536775+1782WP_015080144.1UvrD-helicase domain-containing protein-
ANA_RS110502537082..2537483-402WP_015080145.1hypothetical protein-
ANA_RS110552537606..2537893-288WP_015080146.1type II toxin-antitoxin system HigB family toxin-
ANA_RS110602538462..2538689+228WP_015080147.1virulence associated protein B-
ANA_RS245452538690..2538785+96Protein_2295VapC toxin family PIN domain ribonuclease-
ANA_RS110652539135..2539371+237WP_015080148.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
ANA_RS110702539368..2539631+264WP_015080149.1Txe/YoeB family addiction module toxinToxin
ANA_RS265452539624..2539776+153WP_015080150.1hypothetical protein-
ANA_RS259002539764..2539901+138WP_174782923.1hypothetical protein-
ANA_RS110752539981..2541075+1095WP_015080151.1RIP metalloprotease RseP-
ANA_RS110802541414..2542088+675WP_015080152.1endonuclease III-
ANA_RS110852542192..2542494+303WP_015080153.130S ribosomal protein S14-
ANA_RS110902542614..2542943-330WP_015080154.1hypothetical protein-
ANA_RS110952543002..2543577+576WP_015080155.1leucyl/phenylalanyl-tRNA--protein transferase-
ANA_RS111052543813..2544475-663WP_015080157.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(22-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-69)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10268.77 Da        Isoelectric Point: 9.6964

>T28470 WP_015080149.1 NC_019427:2539368-2539631 [Anabaena sp. 90]
VNWNLVYTKQAQKDAKKLAASNLKDKAQSLLDIIQINPFQNPPPYEKLVGDLERAYSRRINIQHRLVYEVIESENTAKIL
RMWTHYE

Download         Length: 264 bp

>T28470 NC_019427:2539368-2539631 [Anabaena sp. 90]
GTGAATTGGAATTTAGTTTATACTAAACAAGCTCAGAAAGATGCTAAAAAATTGGCTGCAAGTAATTTAAAAGATAAAGC
ACAAAGCTTACTTGATATTATTCAAATCAATCCGTTTCAAAATCCCCCACCTTATGAGAAATTAGTCGGAGATTTAGAAC
GTGCATATTCACGACGGATTAATATTCAACATCGGTTAGTCTATGAAGTAATTGAATCTGAAAATACGGCCAAAATTTTA
CGAATGTGGACTCATTATGAATAG

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8590.67 Da        Isoelectric Point: 3.9169

>AT28470 WP_015080148.1 NC_019427:2539135-2539371 [Anabaena sp. 90]
MISINQAKQQLQDLIDSVNQSHQPIVIAGDNSNAVLLSEADWKSIQETLYLLSIPGIRESIKEGLATPIAECDGELEW

Download         Length: 237 bp

>AT28470 NC_019427:2539135-2539371 [Anabaena sp. 90]
ATGATTTCAATTAATCAAGCAAAACAACAATTACAGGATTTAATTGATTCAGTCAATCAGTCTCATCAACCTATTGTTAT
TGCCGGAGACAATAGCAACGCAGTATTATTGTCTGAAGCAGACTGGAAATCTATCCAAGAAACTCTTTATCTTCTTTCTA
TTCCAGGAATACGGGAATCAATTAAAGAAGGATTAGCAACACCGATTGCAGAATGTGATGGGGAATTAGAGTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBK7W1R6

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A844ILF8

References