Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-RNAII/-
Location 2770331..2770668 Replicon chromosome
Accession NZ_CP128464
Organism Enterococcus faecalis strain RE25

Toxin (Protein)


Gene name txpA Uniprot ID E2Z0W4
Locus tag QSV41_RS14055 Protein ID WP_002381035.1
Coordinates 2770331..2770474 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2770406..2770668 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSV41_RS14035 2766424..2767062 - 639 WP_002378863.1 lytic polysaccharide monooxygenase -
QSV41_RS14040 2767748..2769364 + 1617 WP_002389442.1 phosphatase PAP2/LCP family protein -
QSV41_RS14045 2769699..2769842 + 144 WP_002389461.1 type I toxin-antitoxin system toxin PepG1 -
QSV41_RS14050 2769966..2770100 + 135 WP_153829595.1 putative holin-like toxin -
QSV41_RS14055 2770331..2770474 + 144 WP_002381035.1 putative holin-like toxin Toxin
- 2770406..2770668 - 263 - - Antitoxin
QSV41_RS14060 2770669..2774496 - 3828 WP_010816211.1 WxL domain-containing protein -
QSV41_RS14065 2774483..2774845 - 363 WP_002378868.1 LPXTG cell wall anchor domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5202.20 Da        Isoelectric Point: 10.0041

>T284607 WP_002381035.1 NZ_CP128464:2770331-2770474 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKENNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 263 bp

>AT284607 NZ_CP128464:c2770668-2770406 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTACA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATATCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTTTTCTTTTACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2Z6BWH2

Antitoxin

Download structure file

References