Detailed information of TA system TA284599

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2769699..2769958
• Replicon: chromosome
• Accession: NZ_CP128464
• Organism: Enterococcus faecalis strain RE25

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QSV41_RS14045
• Protein ID: WP_002389461.1
• Coordinates: 2769699..2769842 (+)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2769775..2769958 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QSV41_RS14025	2764814..2765029	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
QSV41_RS14030	2765168..2766160	+	993	WP_002389493.1	biotin--[acetyl-CoA-carboxylase] ligase	-
QSV41_RS14035	2766424..2767062	-	639	WP_002378863.1	lytic polysaccharide monooxygenase	-
QSV41_RS14040	2767748..2769364	+	1617	WP_002389442.1	phosphatase PAP2/LCP family protein	-
QSV41_RS14045	2769699..2769842	+	144	WP_002389461.1	type I toxin-antitoxin system toxin PepG1	Toxin
-	2769775..2769958	-	184	-	-	Antitoxin
QSV41_RS14050	2769966..2770100	+	135	WP_153829595.1	putative holin-like toxin	-
QSV41_RS14055	2770331..2770474	+	144	WP_002381035.1	putative holin-like toxin	-
QSV41_RS14060	2770669..2774496	-	3828	WP_010816211.1	WxL domain-containing protein	-
QSV41_RS14065	2774483..2774845	-	363	WP_002378868.1	LPXTG cell wall anchor domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5450.67 Da
• Isoelectric Point: 11.0942

>T284599 WP_002389461.1 NZ_CP128464:2769699-2769842 [Enterococcus faecalis]
MHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 184 bp

>AT284599 NZ_CP128464:c2769958-2769775 [Enterococcus faecalis]
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAA
TCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin