Detailed information of TA system TA284596

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2678751..2679013
• Replicon: chromosome
• Accession: NZ_CP128464
• Organism: Enterococcus faecalis strain RE25

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QSV41_RS13625
• Protein ID: WP_002367458.1
• Coordinates: 2678870..2679013 (-)
• Length: 48 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2678751..2678937 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QSV41_RS13610	2674208..2676952	+	2745	WP_002411259.1	glycosyl hydrolase family 65 protein	-
QSV41_RS13615	2676967..2677617	+	651	WP_002389419.1	beta-phosphoglucomutase	-
QSV41_RS13620	2678037..2678630	+	594	WP_002389391.1	PBECR4 domain-containing protein	-
-	2678751..2678937	+	187	-	-	Antitoxin
QSV41_RS13625	2678870..2679013	-	144	WP_002367458.1	type I toxin-antitoxin system toxin PepG1	Toxin
QSV41_RS13630	2679245..2680216	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
QSV41_RS13635	2680391..2680828	-	438	WP_002389480.1	peptide-methionine (R)-S-oxide reductase MsrB	-
QSV41_RS13640	2680961..2681515	-	555	WP_002354869.1	Maf family protein	-
QSV41_RS13645	2681540..2683672	-	2133	WP_002389406.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (14-47)

Sequences

Toxin

Protein

• Length: 48 a.a.
• Molecular weight: 5311.50 Da
• Isoelectric Point: 10.8331

>T284596 WP_002367458.1 NZ_CP128464:c2679013-2678870 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 144 bp

Antitoxin

Nucleotide

• Length: 187 bp

>AT284596 NZ_CP128464:2678751-2678937 [Enterococcus faecalis]
TGTGCTAGAATGTAGATGAAAAGAGAGATATGCGTCAACATACCTCTCTAGTGTAGAGCCGTTTGAGACGGTGACCGATT
GTATTATTTAAAAATAACCGTACTGGTCAAAGTAGATGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGTG
CAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin