Detailed information of TA system TA284591

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2607368..2607852
• Replicon: chromosome
• Accession: NZ_CP128464
• Organism: Enterococcus faecalis strain RE25

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QSV41_RS13290
• Protein ID: WP_021164441.1
• Coordinates: 2607368..2607469 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2607643..2607852 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QSV41_RS13265	2602896..2603849	-	954	WP_002370087.1	siderophore ABC transporter substrate-binding protein	-
QSV41_RS13270	2603888..2604643	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QSV41_RS13275	2604640..2605605	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
QSV41_RS13280	2605602..2606549	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
QSV41_RS13285	2606734..2607186	+	453	WP_002389410.1	YueI family protein	-
QSV41_RS13290	2607368..2607469	-	102	WP_021164441.1	putative holin-like toxin	Toxin
-	2607643..2607852	+	210	-	-	Antitoxin
QSV41_RS13295	2607801..2607902	-	102	WP_075551663.1	putative holin-like toxin	-
QSV41_RS13300	2608092..2610362	-	2271	WP_002389492.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QSV41_RS13305	2610533..2611033	+	501	WP_002372831.1	cysteine hydrolase family protein	-
QSV41_RS13310	2611432..2612328	+	897	WP_002389477.1	YitT family protein	-
QSV41_RS13315	2612379..2612777	-	399	WP_002354951.1	glyoxalase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3598.36 Da
• Isoelectric Point: 6.0656

>T284591 WP_021164441.1 NZ_CP128464:c2607469-2607368 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNNKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 210 bp

>AT284591 NZ_CP128464:2607643-2607852 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin