Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 568038..568270 Replicon chromosome
Accession NZ_CP128464
Organism Enterococcus faecalis strain RE25

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag QSV41_RS03240 Protein ID WP_033606579.1
Coordinates 568038..568154 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 568065..568270 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSV41_RS03230 563476..565734 + 2259 WP_002363179.1 DNA helicase PcrA -
QSV41_RS03235 565860..567890 + 2031 WP_002389576.1 NAD-dependent DNA ligase LigA -
QSV41_RS03240 568038..568154 + 117 WP_033606579.1 putative holin-like toxin Toxin
- 568065..568270 - 206 - - Antitoxin
QSV41_RS03245 568472..568777 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
QSV41_RS03250 568777..570246 + 1470 WP_002368026.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
QSV41_RS03255 570246..571676 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
QSV41_RS03260 571695..572783 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4073.99 Da        Isoelectric Point: 5.9482

>T284585 WP_033606579.1 NZ_CP128464:568038-568154 [Enterococcus faecalis]
MLLSVEAALGLMISFAILVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

Antitoxin


Download         Length: 206 bp

>AT284585 NZ_CP128464:c568270-568065 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAATAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTATTGCAAAACTAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References