Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 2006310..2006958 Replicon chromosome
Accession NZ_CP128435
Organism Morganella morganii subsp. morganii strain QLYYMMQL588

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QSV29_RS09735 Protein ID WP_024473062.1
Coordinates 2006614..2006958 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QSV29_RS09730 Protein ID WP_024473063.1
Coordinates 2006310..2006609 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QSV29_RS09710 2001759..2001965 + 207 WP_024473067.1 hypothetical protein -
QSV29_RS09715 2002374..2004761 + 2388 WP_036407993.1 molybdopterin-dependent oxidoreductase -
QSV29_RS09720 2004758..2005387 + 630 WP_214167311.1 dimethylsulfoxide reductase subunit B -
QSV29_RS09725 2005384..2006256 + 873 WP_289647534.1 dimethyl sulfoxide reductase anchor subunit -
QSV29_RS09730 2006310..2006609 - 300 WP_024473063.1 helix-turn-helix transcriptional regulator Antitoxin
QSV29_RS09735 2006614..2006958 - 345 WP_024473062.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QSV29_RS09740 2007114..2007281 - 168 WP_289647535.1 hypothetical protein -
QSV29_RS09745 2007286..2010372 - 3087 WP_205501287.1 efflux RND transporter permease subunit -
QSV29_RS09750 2010369..2011457 - 1089 WP_205501288.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-83)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13172.07 Da        Isoelectric Point: 9.3450

>T284566 WP_024473062.1 NZ_CP128435:c2006958-2006614 [Morganella morganii subsp. morganii]
VRTVLLTDYFNEWLSGQDTRMQEKVLASLGNLEIYGPVLTRPYVDTVKNSQYPNMKELRIWHAGRAIRAFFAFDSERQAI
VLCAGDKGKNKRFYQTMIRIADEQFSSYLAAAKE

Download         Length: 345 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11208.05 Da        Isoelectric Point: 8.6587

>AT284566 WP_024473063.1 NZ_CP128435:c2006609-2006310 [Morganella morganii subsp. morganii]
MKTLQEVIAAQPPESRERIKRLTDELVLETGLQLLREELHISQKMLATNLGISQPAVTQIEQRGNDIKLATLKRYIEAMG
GTLRLTIELPTGDNRVFRV

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References