Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2176175..2176438 Replicon chromosome
Accession NZ_CP128389
Organism Staphylococcus aureus strain 21-024

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag QTN91_RS10425 Protein ID WP_001802298.1
Coordinates 2176175..2176279 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2176274..2176438 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTN91_RS10390 (QTN91_10390) 2172074..2172682 + 609 WP_000101714.1 TIR domain-containing protein -
QTN91_RS10395 (QTN91_10395) 2172972..2173754 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
QTN91_RS10400 (QTN91_10400) 2173822..2174679 + 858 WP_000370942.1 HAD family hydrolase -
QTN91_RS10405 (QTN91_10405) 2174809..2174901 - 93 WP_000220902.1 hypothetical protein -
QTN91_RS10410 (QTN91_10410) 2175337..2175495 - 159 WP_001792784.1 hypothetical protein -
QTN91_RS10415 (QTN91_10415) 2175488..2175658 - 171 WP_001807897.1 hypothetical protein -
QTN91_RS10420 (QTN91_10420) 2175916..2176014 + 99 Protein_2046 resolvase -
QTN91_RS10425 (QTN91_10425) 2176175..2176279 + 105 WP_001802298.1 hypothetical protein Toxin
- 2176274..2176438 - 165 - - Antitoxin
QTN91_RS10435 (QTN91_10435) 2176777..2177868 - 1092 WP_000495673.1 hypothetical protein -
QTN91_RS10440 (QTN91_10440) 2178134..2179114 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
QTN91_RS10445 (QTN91_10445) 2179116..2179436 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
QTN91_RS10450 (QTN91_10450) 2179588..2180253 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T284538 WP_001802298.1 NZ_CP128389:2176175-2176279 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 165 bp

>AT284538 NZ_CP128389:c2176438-2176274 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References