Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1880462..1880646 Replicon chromosome
Accession NZ_CP128389
Organism Staphylococcus aureus strain 21-024

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag QTN91_RS08865 Protein ID WP_000482647.1
Coordinates 1880462..1880569 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1880586..1880646 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTN91_RS08840 (QTN91_08840) 1875819..1876292 + 474 WP_000456489.1 GyrI-like domain-containing protein -
QTN91_RS08845 (QTN91_08845) 1876415..1877626 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
QTN91_RS08850 (QTN91_08850) 1877814..1878473 - 660 WP_000831300.1 hypothetical protein -
QTN91_RS08855 (QTN91_08855) 1878533..1879675 - 1143 WP_001176859.1 glycerate kinase -
QTN91_RS08860 (QTN91_08860) 1879942..1880328 + 387 WP_000779355.1 flippase GtxA -
QTN91_RS08865 (QTN91_08865) 1880462..1880569 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1880586..1880646 - 61 - - Antitoxin
QTN91_RS08870 (QTN91_08870) 1881273..1883036 + 1764 WP_001064818.1 ABC transporter ATP-binding protein -
QTN91_RS08875 (QTN91_08875) 1883061..1884794 + 1734 WP_000486511.1 ABC transporter ATP-binding protein -
QTN91_RS08880 (QTN91_08880) 1885025..1885192 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T284537 WP_000482647.1 NZ_CP128389:1880462-1880569 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT284537 NZ_CP128389:c1880646-1880586 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References