Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2181469..2181748 Replicon chromosome
Accession NZ_CP128388
Organism Staphylococcus aureus strain 21-074

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag QTN92_RS10400 Protein ID WP_001802298.1
Coordinates 2181469..2181573 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2181569..2181748 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTN92_RS10375 (QTN92_10375) 2177368..2177919 + 552 WP_289211166.1 TIR domain-containing protein -
QTN92_RS10380 (QTN92_10380) 2178266..2179048 + 783 WP_000908191.1 ABC transporter ATP-binding protein -
QTN92_RS10385 (QTN92_10385) 2179116..2179973 + 858 WP_000370942.1 HAD family hydrolase -
QTN92_RS10390 (QTN92_10390) 2180631..2180789 - 159 WP_001792784.1 hypothetical protein -
QTN92_RS10395 (QTN92_10395) 2181210..2181308 + 99 Protein_2041 resolvase -
QTN92_RS10400 (QTN92_10400) 2181469..2181573 + 105 WP_001802298.1 hypothetical protein Toxin
- 2181569..2181748 - 180 - - Antitoxin
QTN92_RS10410 (QTN92_10410) 2182137..2183228 - 1092 WP_000495673.1 hypothetical protein -
QTN92_RS10415 (QTN92_10415) 2183494..2184474 - 981 WP_000019735.1 CDF family zinc efflux transporter CzrB -
QTN92_RS10420 (QTN92_10420) 2184476..2184796 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
QTN92_RS10425 (QTN92_10425) 2184948..2185613 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T284528 WP_001802298.1 NZ_CP128388:2181469-2181573 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

Antitoxin


Download         Length: 180 bp

>AT284528 NZ_CP128388:c2181748-2181569 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References