Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1885688..1885872 Replicon chromosome
Accession NZ_CP128388
Organism Staphylococcus aureus strain 21-074

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag QTN92_RS08845 Protein ID WP_000482647.1
Coordinates 1885688..1885795 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1885812..1885872 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QTN92_RS08820 (QTN92_08820) 1881045..1881518 + 474 WP_000456489.1 GyrI-like domain-containing protein -
QTN92_RS08825 (QTN92_08825) 1881641..1882852 - 1212 WP_001191974.1 multidrug effflux MFS transporter -
QTN92_RS08830 (QTN92_08830) 1883040..1883699 - 660 WP_000831300.1 hypothetical protein -
QTN92_RS08835 (QTN92_08835) 1883759..1884901 - 1143 WP_001176859.1 glycerate kinase -
QTN92_RS08840 (QTN92_08840) 1885168..1885554 + 387 WP_000779355.1 flippase GtxA -
QTN92_RS08845 (QTN92_08845) 1885688..1885795 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1885812..1885872 - 61 - - Antitoxin
QTN92_RS08850 (QTN92_08850) 1886499..1888262 + 1764 WP_001064818.1 ABC transporter ATP-binding protein -
QTN92_RS08855 (QTN92_08855) 1888287..1890020 + 1734 WP_000486511.1 ABC transporter ATP-binding protein -
QTN92_RS08860 (QTN92_08860) 1890251..1890418 + 168 WP_001798790.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T284526 WP_000482647.1 NZ_CP128388:1885688-1885795 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp


Antitoxin


Download         Length: 61 bp

>AT284526 NZ_CP128388:c1885872-1885812 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7


Antitoxin

Download structure file

References